8U3C
TRPV1 in nanodisc bound with PI-Br4 bound in Conformation 2 (monomer)
Summary for 8U3C
Entry DOI | 10.2210/pdb8u3c/pdb |
EMDB information | 41857 |
Descriptor | Transient receptor potential cation channel subfamily V member 1, (2S)-2-[(9,10-dibromooctadecanoyl)oxy]-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9R,10S)-9,10-dibromooctadecanoate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (6 entities in total) |
Functional Keywords | trpv1 in nanodisc bound with pi-br4 bound in conformation 2 (monomer), membrane protein |
Biological source | Rattus norvegicus (Norway rat) |
Total number of polymer chains | 2 |
Total formula weight | 188006.18 |
Authors | Arnold, W.R.,Julius, D.,Cheng, Y. (deposition date: 2023-09-07, release date: 2024-05-08, Last modification date: 2024-10-02) |
Primary citation | Arnold, W.R.,Mancino, A.,Moss 3rd, F.R.,Frost, A.,Julius, D.,Cheng, Y. Structural basis of TRPV1 modulation by endogenous bioactive lipids. Nat.Struct.Mol.Biol., 31:1377-1385, 2024 Cited by PubMed: 38698206DOI: 10.1038/s41594-024-01299-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.3 Å) |
Structure validation
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