8U3C

TRPV1 in nanodisc bound with PI-Br4 bound in Conformation 2 (monomer)

8U3C の概要

• エントリーDOI: 10.2210/pdb8u3c/pdb
• EMDBエントリー: 41857
• 分子名称: Transient receptor potential cation channel subfamily V member 1, (2S)-2-[(9,10-dibromooctadecanoyl)oxy]-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9R,10S)-9,10-dibromooctadecanoate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (6 entities in total)
• 機能のキーワード: trpv1 in nanodisc bound with pi-br4 bound in conformation 2 (monomer), membrane protein
• 由来する生物種: Rattus norvegicus (Norway rat)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 188006.18

構造登録者

Arnold, W.R.,Julius, D.,Cheng, Y. (登録日: 2023-09-07, 公開日: 2024-05-08, 最終更新日: 2024-10-02)

• 主引用文献: Arnold, W.R.,Mancino, A.,Moss 3rd, F.R.,Frost, A.,Julius, D.,Cheng, Y.; Structural basis of TRPV1 modulation by endogenous bioactive lipids.; Nat.Struct.Mol.Biol., 31:1377-1385, 2024; PubMed: 38698206; DOI: 10.1038/s41594-024-01299-2

実験手法

ELECTRON MICROSCOPY (2.3 Å)