8U1L
Cryo-EM structure of the RAF1-HSP90-CDC37 complex in the closed state
Summary for 8U1L
Entry DOI | 10.2210/pdb8u1l/pdb |
EMDB information | 41816 41817 41818 |
Descriptor | Heat shock protein 83, RAF proto-oncogene serine/threonine-protein kinase, Hsp90 co-chaperone Cdc37, N-terminally processed, ... (5 entities in total) |
Functional Keywords | craf, raf1, hsp90, cdc37, signaling protein-chaperone complex, signaling protein/chaperone |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 286351.05 |
Authors | |
Primary citation | Finci, L.I.,Chakrabarti, M.,Gulten, G.,Finney, J.,Grose, C.,Fox, T.,Yang, R.,Nissley, D.V.,McCormick, F.,Esposito, D.,Balius, T.E.,Simanshu, D.K. Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements. Commun Biol, 7:260-260, 2024 Cited by PubMed: 38431713DOI: 10.1038/s42003-024-05959-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.7 Å) |
Structure validation
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