8TWX

Synthesis and Evaluation of Diaryl Ether Modulators of the Leukotriene A4 Hydrolase Aminopeptidase Activity

Summary for 8TWX

• Entry DOI: 10.2210/pdb8twx/pdb
• Descriptor: Leukotriene A-4 hydrolase, 5-[4-(4-chlorophenoxy)phenyl]-1H-pyrazol-3-amine, ZINC ION, ... (4 entities in total)
• Functional Keywords: leukotriene a4 hydrolase, 4mdm, aminipeptidase, activator, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 207447.86

Authors

Lee, K.H.,Lee, S.H.,Paige, M.,Noble, S.M. (deposition date: 2023-08-21, release date: 2024-08-28)

• Primary citation: Lee, K.H.,Lee, S.H.,Paige, M.,Noble, S.M.; Synthesis and Evaluation of Diaryl Ether Modulators of the Leukotriene A4 Hydrolase Aminopeptidase Activity; To be published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)