8TWX
Synthesis and Evaluation of Diaryl Ether Modulators of the Leukotriene A4 Hydrolase Aminopeptidase Activity
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Leukotriene A-4 hydrolase | polymer | 607 | 68893.4 | 3 | UniProt (P09960) Pfam (PF17900) Pfam (PF01433) Pfam (PF09127) | Homo sapiens (human) | |
| 2 | D, F (A, B) | 5-[4-(4-chlorophenoxy)phenyl]-1H-pyrazol-3-amine | non-polymer | 285.7 | 2 | Chemie (VI7) | |||
| 3 | E, G, H (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | I, J, K (A, B, C) | water | water | 18.0 | 485 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 206680.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 767.7 | |
| All* | Total formula weight | 207447.9 |
