8TRC

mGluR3 in the presence of the antagonist LY 341495 and positive allosteric modulator VU6023326

Summary for 8TRC

• Entry DOI: 10.2210/pdb8trc/pdb
• EMDB information: 41577
• Descriptor: Metabotropic glutamate receptor 3, 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine (2 entities in total)
• Functional Keywords: gpcr, synaptic protein, membrane protein
• Biological source: Rattus norvegicus (Norway rat)
• Total number of polymer chains: 2
• Total formula weight: 207029.85

Authors

Strauss, A.,Levitz, J. (deposition date: 2023-08-09, release date: 2024-07-31)

• Primary citation: Strauss, A.,Gonzalez-Hernandez, A.J.,Lee, J.,Abreu, N.,Selvakumar, P.,Salas-Estrada, L.,Kristt, M.,Marx, D.C.,Gilliland, K.,Melancon, B.J.,Filizola, M.,Meyerson, J.,Levitz, J.; Structural basis of allosteric modulation of metabotropic glutamate receptor activation and desensitization.; Biorxiv, 2023; PubMed: 37645747; DOI: 10.1101/2023.08.13.552748

Experimental method

ELECTRON MICROSCOPY (3.3 Å)