8TQ1

HIV-1 BG505 Env SOSIP in complex with bovine Fab Bess4 and non-human primate Fab RM20A3

8TQ1 の概要

• エントリーDOI: 10.2210/pdb8tq1/pdb
• EMDBエントリー: 41498
• 分子名称: HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp120, Transmembrane protein gp41, NHP RM20A3 Fab heavy chain, ... (9 entities in total)
• 機能のキーワード: sosip, apex, broadly neutralizing antibody, env, hiv-1, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 13
• 化学式量合計: 340440.98

構造登録者

Ozorowski, G.,Lee, W.H.,Ward, A.B. (登録日: 2023-08-06, 公開日: 2024-08-07)

• 主引用文献: Altman, P.,Ozorowski, G.; Immunization of cows with HIV Envelope trimers generates broadly neutralizing antibodies to the V2-apex as well as the CD4 binding site from the ultra-long CDRH3 repertoire; To Be Published,

実験手法

ELECTRON MICROSCOPY (3.3 Å)