8TO4
EGFR(T790M/V948R) in complex with the allosteric inhibitor FRF-06-057
Summary for 8TO4
Entry DOI | 10.2210/pdb8to4/pdb |
Descriptor | Epidermal growth factor receptor, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total) |
Functional Keywords | kinase, inhibitor, cancer, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 152766.25 |
Authors | Chitnis, S.P.,Deng, M.Q.,Pham, C.P.,Heppner, D.E. (deposition date: 2023-08-02, release date: 2024-08-28) |
Primary citation | Chitnis, S.P.,Pham, C.D.,Deng, M.Q.,Heppner, D.E. EGFR(T790M/V948R) in complex with the allosteric inhibitor FRF-06-057 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.99 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)