8TGA

Complex of NPR1 ectodomain and REGN5381 Fab in an active-like state with no ANP bound

Summary for 8TGA

• Entry DOI: 10.2210/pdb8tga/pdb
• EMDB information: 41234
• Descriptor: Atrial natriuretic peptide receptor 1, REGN5381 Fab light chain, REGN5381 Fab heavy chain (3 entities in total)
• Functional Keywords: atrial natriuretic peptide, antibody, activator, pulmonary hypertension, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 200812.78

Authors

Franklin, M.C.,Romero Hernandez, A. (deposition date: 2023-07-12, release date: 2024-07-17)

• Primary citation: Franklin, M.C.,Romero Hernandez, A.; Complex of NPR1 ectodomain and REGN5381 Fab in an active-like state with no ANP bound; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.65 Å)