8T9G

Automethylated PRC2 dimer bound to nucleosome

This is a non-PDB format compatible entry.

Summary for 8T9G

• Entry DOI: 10.2210/pdb8t9g/pdb
• EMDB information: 41110
• Descriptor: Polycomb protein SUZ12, Histone H2B 1.1, DNA (226-MER), ... (13 entities in total)
• Functional Keywords: histone methyl transferase, gene repression, epigenetics, chromatin, gene regulation
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 21
• Total formula weight: 825687.67

Authors

Sauer, P.V.,Pavlenko, E.,Nogales, E.,Poepsel, S. (deposition date: 2023-06-23, release date: 2024-09-25, Last modification date: 2024-10-09)

• Primary citation: Sauer, P.V.,Pavlenko, E.,Cookis, T.,Zirden, L.C.,Renn, J.,Singhal, A.,Hunold, P.,Hoehne-Wiechmann, M.N.,van Ray, O.,Kaschani, F.,Kaiser, M.,Hansel-Hertsch, R.,Sanbonmatsu, K.Y.,Nogales, E.,Poepsel, S.; Activation of automethylated PRC2 by dimerization on chromatin.; Mol.Cell, 2024; PubMed: 39303719; DOI: 10.1016/j.molcel.2024.08.025

Experimental method

ELECTRON MICROSCOPY (6.2 Å)