Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, Q (B, G) | Polycomb protein SUZ12 | polymer | 619 | 72266.4 | 2 | UniProt (Q15022) Pfam (PF09733) | Homo sapiens (human) | Chromatin precipitated E2F target 9 protein,ChET 9 protein,Joined to JAZF1 protein,Suppressor of zeste 12 protein homolog |
| 2 | B, R (C, I) | Histone-lysine N-methyltransferase EZH2 | polymer | 753 | 86175.0 | 2 | UniProt (Q15910) Pfam (PF11616) Pfam (PF18118) Pfam (PF21358) Pfam (PF18264) Pfam (PF00856) | Homo sapiens (human) | ENX-1,Enhancer of zeste homolog 2,Lysine N-methyltransferase 6 |
| 3 | C, S (F, K) | Polycomb protein EED | polymer | 441 | 50267.7 | 2 | UniProt (O75530) Pfam (PF00400) | Homo sapiens (human) | hEED,Embryonic ectoderm development protein,WD protein associating with integrin cytoplasmic tails 1,WAIT-1 |
| 4 | D, T (L, O) | Histone-binding protein RBBP4 | polymer | 425 | 47709.5 | 2 | UniProt (Q09028) Pfam (PF12265) Pfam (PF00400) | Homo sapiens (human) | Chromatin assembly factor 1 subunit C,CAF-1 subunit C,Chromatin assembly factor I p48 subunit,CAF-I 48 kDa subunit,CAF-I p48,Nucleosome-remodeling factor subunit RBAP48,Retinoblastoma-binding protein 4,RBBP-4,Retinoblastoma-binding protein p48 |
| 5 | E, U (M, Y) | Zinc finger protein AEBP2 | polymer | 303 | 34183.2 | 2 | UniProt (Q6ZN18) | Homo sapiens (human) | Adipocyte enhancer-binding protein 2,AE-binding protein 2 |
| 6 | F, N (A, W) | Histone H3.2 | polymer | 136 | 15435.1 | 2 | UniProt (P84233) Pfam (PF00125) | Xenopus laevis (African clawed frog) | |
| 7 | G (H) | DNA (226-MER) | polymer | 215 | 66539.3 | 1 | synthetic construct | ||
| 8 | H, O (J, X) | Histone H4 | polymer | 106 | 11625.6 | 2 | UniProt (P62799) Pfam (PF15511) | Xenopus laevis (African clawed frog) | |
| 9 | I, L (R, U) | Histone H2A type 1 | polymer | 133 | 14355.7 | 2 | UniProt (P06897) Pfam (PF00125) Pfam (PF16211) | Xenopus laevis (African clawed frog) | |
| 10 | J, M (S, V) | Histone H2B 1.1 | polymer | 123 | 13655.9 | 2 | UniProt (P02281) Pfam (PF00125) | Xenopus laevis (African clawed frog) | H2B1.1 |
| 11 | K (T) | DNA (226-MER) | polymer | 215 | 65905.9 | 1 | synthetic construct | ||
| 12 | P (E) | activating methylated peptide | polymer | 12 | 1125.4 | 1 | Homo sapiens (human) | ||
| 13 | V, W (C, I) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) |
Sequence modifications
B, G: 68 - 685 (UniProt: Q15022)
C, I: 2 - 751 (UniProt: Q15910)
M, Y: 9 - 309 (UniProt: Q6ZN18)
A, W: 0 - 135 (UniProt: P84233)
J, X: 0 - 102 (UniProt: P62799)
R, U: 0 - 129 (UniProt: P06897)
S, V: 1 - 122 (UniProt: P02281)
| PDB | External Database | Details |
|---|---|---|
| Met 67 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Asn 0 | - | expression tag |
| Ala 1 | - | expression tag |
| Ala 14 | Cys 14 | conflict |
| Cys 15 | Trp 15 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser 7 | - | expression tag |
| Asn 8 | - | expression tag |
| Ala 9 | Met 1 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 102 | Gly 103 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser 103 | - | expression tag |
| Ser 104 | - | expression tag |
| Gly 105 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser -3 | - | expression tag |
| Asn -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Arg 99 | Gly 100 | conflict |
| Cys 119 | Lys 120 | conflict |
| Ser 123 | Ala 124 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Thr 29 | Ser 33 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 21 |
| Total formula weight | 824918.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 768.8 | |
| All* | Total formula weight | 825687.7 |
