8T7G
Structure of the CK variant of Fab F1 (FabC-F1)
Summary for 8T7G
Entry DOI | 10.2210/pdb8t7g/pdb |
Related | 8T7F 8T7I 8T9B |
Descriptor | CK variant of Fab F1 heavy chain, CK variant of Fab F1 light chain, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | enhanced crystallization, epha2 binding, engineered protein, fab, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 49042.97 |
Authors | Singer, A.U.,Bruce, H.A.,Blazer, L.,Adams, J.J.,Sicheri, F.,Sidhu, S.S. (deposition date: 2023-06-20, release date: 2023-11-22, Last modification date: 2024-01-10) |
Primary citation | Bruce, H.A.,Singer, A.U.,Filippova, E.V.,Blazer, L.L.,Adams, J.J.,Enderle, L.,Ben-David, M.,Radley, E.H.,Mao, D.Y.L.,Pau, V.,Orlicky, S.,Sicheri, F.,Kurinov, I.,Atwell, S.,Kossiakoff, A.A.,Sidhu, S.S. Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes. Protein Sci., 33:e4824-e4824, 2024 Cited by PubMed: 37945533DOI: 10.1002/pro.4824 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report