8SW9

Plasmodium falciparum M17 (A460S) mutant

Summary for 8SW9

• Entry DOI: 10.2210/pdb8sw9/pdb
• Descriptor: Leucine aminopeptidase, ZINC ION, CARBONATE ION, ... (6 entities in total)
• Functional Keywords: metallo-exopeptidase, m17 aminopeptidase, leucine aminopeptidase, malaria, aminopeptidase, hydrolase
• Biological source: Plasmodium falciparum (malaria parasite P. falciparum)
• Total number of polymer chains: 12
• Total formula weight: 713388.23

Authors

McGowan, S.,Suraweera, C.,Drinkwater, N. (deposition date: 2023-05-17, release date: 2024-04-24)

• Primary citation: de Koning-Ward, T.F.,Drinkwater, N.,Edgar, R.C.S.,McGowan, S.,Scammells, P.J.; Characterisation of a novel antimalarial agent targeting haemaglobin digestion that shows cross-species reactivity and excellent in vivo properties.; Mbio, 2024

Experimental method

X-RAY DIFFRACTION (2.6 Å)