8SW9

Plasmodium falciparum M17 (A460S) mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Leucine aminopeptidase	polymer	528	58725.0	12	UniProt (Q8IL11) Pfam (PF00883)	Plasmodium falciparum (malaria parasite P. falciparum)	PfLAP,M17 leucyl aminopeptidase,PfA-M17,PfM17LAP
2	AB, CC, DC, GA, GB... (G, L, D, H, I...)	ZINC ION	non-polymer		65.4	24	Chemie (ZN)
3	AA, EC, IA, IB, NB... (C, L, D, H, I...)	CARBONATE ION	non-polymer		60.0	12	Chemie (CO3)
4	AC, BA, BB, BC, FA... (K, C, G, L, D...)	SULFATE ION	non-polymer		96.1	17	Chemie (SO4)
5	CA, CB, DA, DB, EA... (C, G, L, H, D...)	PENTAETHYLENE GLYCOL	non-polymer		238.3	20	Chemie (1PE)
6	HC, IC, JC, KC, LC... (A, B, C, D, E...)	water	water		18.0	1056	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 84 - 605 (UniProt: Q8IL11)

PDB	External Database	Details
Gln 152	Asn 152	engineered mutation
Ser 460	Ala 460	engineered mutation
Gln 515	Asn 515	engineered mutation
Gln 546	Asn 546	engineered mutation
His 606	-	expression tag
His 607	-	expression tag
His 608	-	expression tag
His 609	-	expression tag
His 610	-	expression tag
His 611	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	704699.7
Non-Polymers*	Number of molecules	73
	Total formula weight	8688.6
All*	Total formula weight	713388.2

*Water molecules are not included.