8STD
S127A variant of LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with authentic substrate NaAD and soaked with CS2
Summary for 8STD
Entry DOI | 10.2210/pdb8std/pdb |
Descriptor | Pyridinium-3,5-biscarboxylic acid mononucleotide synthase, MAGNESIUM ION, NICOTINIC ACID ADENINE DINUCLEOTIDE (3 entities in total) |
Functional Keywords | carboxylase, hydrolase, lyase (carbon-carbon), lyase |
Biological source | Lactiplantibacillus plantarum WCFS1 |
Total number of polymer chains | 6 |
Total formula weight | 163176.61 |
Authors | Chatterjee, S.,Rankin, J.A.,Hu, J.,Hausinger, R.P. (deposition date: 2023-05-10, release date: 2023-12-27) |
Primary citation | Chatterjee, S.,Nevarez, J.L.,Rankin, J.A.,Hu, J.,Hausinger, R.P. Structure of the LarB-Substrate Complex and Identification of a Reaction Intermediate during Nickel-Pincer Nucleotide Cofactor Biosynthesis. Biochemistry, 62:3096-3104, 2023 Cited by PubMed: 37831946DOI: 10.1021/acs.biochem.3c00242 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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