8STD

S127A variant of LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with authentic substrate NaAD and soaked with CS2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0006189	biological_process	'de novo' IMP biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016787	molecular_function	hydrolase activity
B	0005886	cellular_component	plasma membrane
B	0006189	biological_process	'de novo' IMP biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016787	molecular_function	hydrolase activity
C	0005886	cellular_component	plasma membrane
C	0006189	biological_process	'de novo' IMP biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016787	molecular_function	hydrolase activity
D	0005886	cellular_component	plasma membrane
D	0006189	biological_process	'de novo' IMP biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016787	molecular_function	hydrolase activity
E	0005886	cellular_component	plasma membrane
E	0006189	biological_process	'de novo' IMP biosynthetic process
E	0016740	molecular_function	transferase activity
E	0016787	molecular_function	hydrolase activity
F	0005886	cellular_component	plasma membrane
F	0006189	biological_process	'de novo' IMP biosynthetic process
F	0016740	molecular_function	transferase activity
F	0016787	molecular_function	hydrolase activity

Functional Information from PROSITE/UniProt

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. LdrqrrngfpEviYGAGKTATqIVGiVQA

Chain	Residue	Details
A	LEU40-ALA68

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	252
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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