8SQZ

Structure of human ULK1 complex core (2:2:2 stoichiometry) in the PI3KC3-C1 mixture

Summary for 8SQZ

• Entry DOI: 10.2210/pdb8sqz/pdb
• Related: 8SOI 8SOR 8SRM 8SRQ
• EMDB information: 40715
• Descriptor: RB1-inducible coiled-coil protein 1, Serine/threonine-protein kinase ULK1, Autophagy-related protein 13 (3 entities in total)
• Functional Keywords: autophagy, protein kinase, complex, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 229225.49

Authors

Chen, M.,Hurley, J.H. (deposition date: 2023-05-04, release date: 2023-06-21, Last modification date: 2024-06-19)

• Primary citation: Chen, M.,Ren, X.,Cook, A.,Hurley, J.H.; Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex; bioRxiv, 2023; DOI: 10.1101/2023.06.01.543278

Experimental method

ELECTRON MICROSCOPY (5.85 Å)