8SQH

SpRY-Cas9:gRNA complex targeting TTC PAM DNA

Summary for 8SQH

• Entry DOI: 10.2210/pdb8sqh/pdb
• Related: 8SPQ
• EMDB information: 40681 40705
• Descriptor: CRISPR-associated endonuclease Cas9/Csn1, gRNA, TS, ... (6 entities in total)
• Functional Keywords: spry-cas9, crispr, cas9, immune system, immune system-hydrolase complex, immune system/hydrolase
• Biological source: Streptococcus pyogenes; More
• Total number of polymer chains: 5
• Total formula weight: 217679.80

Authors

Hibshman, G.N.,Bravo, J.P.K.,Taylor, D.W. (deposition date: 2023-05-04, release date: 2024-05-01, Last modification date: 2024-05-15)

• Primary citation: Hibshman, G.N.,Bravo, J.P.K.,Hooper, M.M.,Dangerfield, T.L.,Zhang, H.,Finkelstein, I.J.,Johnson, K.A.,Taylor, D.W.; Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.; Nat Commun, 15:3663-3663, 2024; PubMed: 38688943; DOI: 10.1038/s41467-024-47830-3

Experimental method

ELECTRON MICROSCOPY (3.69 Å)