8SNK
Crystal structure of metformin hydrolase (MfmAB) from Pseudomonas mendocina sp. MET-2 mutant (MfmA/D188N)
Summary for 8SNK
| Entry DOI | 10.2210/pdb8snk/pdb |
| Related | 8SNF |
| Descriptor | metformin hydrolase subunit A, metformin hydrolase subunit B, ZINC ION, ... (4 entities in total) |
| Functional Keywords | ureohydrolase, metformin, metalloenzyme, guanylurea, hydrolase |
| Biological source | Pseudomonas mendocina More |
| Total number of polymer chains | 6 |
| Total formula weight | 233673.93 |
| Authors | Tassoulas, L.J.,Rankin, J.A.,Elias, M.H.,Wackett, L.P. (deposition date: 2023-04-27, release date: 2024-03-06) |
| Primary citation | Tassoulas, L.J.,Rankin, J.A.,Elias, M.H.,Wackett, L.P. Dinickel enzyme evolved to metabolize the pharmaceutical metformin and its implications for wastewater and human microbiomes. Proc.Natl.Acad.Sci.USA, 121:e2312652121-e2312652121, 2024 Cited by PubMed: 38408229DOI: 10.1073/pnas.2312652121 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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