8SE3
Structure of Full-length Human Protein Kinase C Beta 1 (PKCBI) in the Active Conformation
Summary for 8SE3
Entry DOI | 10.2210/pdb8se3/pdb |
Related | 8SE1 |
Descriptor | Protein kinase C beta type, GLYCEROL, ZINC ION, ... (4 entities in total) |
Functional Keywords | protein kinase c beta, kinase, phosphorylation, pkcb, pkc, kinase signalling, prkcb, signaling protein, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 77918.94 |
Authors | Cong, A.T.Q.,Witter, T.L.,Bruinsma, E.S.,Jayaraman, S.,Hawse, J.R.,Goetz, M.P.,Schellenberg, M.J. (deposition date: 2023-04-07, release date: 2025-08-20) |
Primary citation | Cong, A.T.Q.,Witter, T.L.,Bruinsma, E.S.,Bhattacharya, S.S.,Jayaraman, S.,Dugan, M.B.,Paluncic, J.,Kuffel, M.J.,Farmakes, J.,Alvey, J.,Wu, X.,Fields, A.P.,Pandey, A.,Hawse, J.R.,Goetz, M.P.,Schellenberg, M.J. Molecular Basis of Allosteric Regulation and Pharmaceutical Targeting of Protein Kinase C b To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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