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8SE3

Structure of Full-length Human Protein Kinase C Beta 1 (PKCBI) in the Active Conformation

Summary for 8SE3
Entry DOI10.2210/pdb8se3/pdb
Related8SE1
DescriptorProtein kinase C beta type, GLYCEROL, ZINC ION, ... (4 entities in total)
Functional Keywordsprotein kinase c beta, kinase, phosphorylation, pkcb, pkc, kinase signalling, prkcb, signaling protein, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight77918.94
Authors
Cong, A.T.Q.,Witter, T.L.,Bruinsma, E.S.,Jayaraman, S.,Hawse, J.R.,Goetz, M.P.,Schellenberg, M.J. (deposition date: 2023-04-07, release date: 2025-08-20)
Primary citationCong, A.T.Q.,Witter, T.L.,Bruinsma, E.S.,Bhattacharya, S.S.,Jayaraman, S.,Dugan, M.B.,Paluncic, J.,Kuffel, M.J.,Farmakes, J.,Alvey, J.,Wu, X.,Fields, A.P.,Pandey, A.,Hawse, J.R.,Goetz, M.P.,Schellenberg, M.J.
Molecular Basis of Allosteric Regulation and Pharmaceutical Targeting of Protein Kinase C b
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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