8S7O

M. tuberculosis gyrase holocomplex with 150 bp DNA and BDM71403

This is a non-PDB format compatible entry.

Summary for 8S7O

• Entry DOI: 10.2210/pdb8s7o/pdb
• Related: 8S7K
• EMDB information: 19782
• Descriptor: DNA gyrase subunit A, DNA gyrase subunit B, DNA (5'-D(*CP*CP*GP*GP*AP*AP*GP*GP*GP*GP*TP*AP*AP*TP*AP*CP*T)-3'), ... (5 entities in total)
• Functional Keywords: mycobacterium tuberculosis, dna gyrase, novel bacterial topoisomerase ii inhibitors, antibiotic resistance, structure-activity relation, dna binding protein
• Biological source: Mycobacterium tuberculosis; More
• Total number of polymer chains: 6
• Total formula weight: 426520.63

Authors

Gedeon, A.,Yab, E.,Dinut, A.,Sadowski, E.,Capton, E.,Dreneau, A.,Gioia, B.,Piveteau, C.,Djaout, K.,Lecat, E.,Wehenkel, A.M.,Gubellini, F.,Mechaly, A.,Alzari, P.M.,Deprez, B.,Baulard, A.,Aubry, A.,Willand, N.,Petrella, S. (deposition date: 2024-03-04, release date: 2025-03-19)

• Primary citation: Gedeon, A.,Yab, E.,Dinut, A.,Sadowski, E.,Capton, E.,Dreneau, A.,Gioia, B.,Piveteau, C.,Djaout, K.,Lecat, E.,Wehenkel, A.M.,Gubellini, F.,Mechaly, A.,Alzari, P.M.,Deprez, B.,Baulard, A.,Aubry, A.,Willand, N.,Petrella, S.; M. tuberculosis gyrase holocomplex with 150 bp DNA and BDM71403; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.8 Å)