8S0R

Cryo-EM structure of CAK modified by covalent inhibitor SY-1365

This is a non-PDB format compatible entry.

Summary for 8S0R

• Entry DOI: 10.2210/pdb8s0r/pdb
• EMDB information: 19627
• Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... (5 entities in total)
• Functional Keywords: kinase, covalent inhibitor, transcription, cell cycle
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 87907.77

Authors

Feng, J.,Koh, A.F.,Kotecha, A.,Greber, B.J. (deposition date: 2024-02-14, release date: 2024-12-25)

• Primary citation: Jones, T.,Feng, J.,Koh, A.F.,Cronin, N.B.,Kotecha, A.,Marineau, J.,Greber, B.J.,Taatjes, D.; Cryo-EM structure of CAK modified by covalent inhibitor SY-1365; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.4 Å)