8S0L
Crystal structure of the TMPRSS2 zymogen in complex with the nanobody A07
Summary for 8S0L
Entry DOI | 10.2210/pdb8s0l/pdb |
Related | 8S0M 8S0N |
Descriptor | Transmembrane protease serine 2, Nanobody A07, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | protease, nanobody, inhibitor, zymogen, protein binding, protease-nanobody inhibitor complex, protease/nanobody inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 59970.97 |
Authors | Duquerroy, S.,Fernandez, I.,Rey, F. (deposition date: 2024-02-14, release date: 2024-06-26, Last modification date: 2024-09-04) |
Primary citation | Fernandez, I.,Saunders, N.,Duquerroy, S.,Bolland, W.H.,Arbabian, A.,Baquero, E.,Blanc, C.,Lafaye, P.,Haouz, A.,Buchrieser, J.,Schwartz, O.,Rey, F.A. Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus. Cell, 187:4246-4260.e16, 2024 Cited by PubMed: 38964326DOI: 10.1016/j.cell.2024.06.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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