8RZI

ZgGH129 from Zobellia galactanivorans soaked with 1,2-diF-ADG (3,6-Anhydro-2-deoxy-2-fluoro-a-D-galactopyranosyl fluoride) resulting in a trapped glycosyl-enzyme intermediate.

This is a non-PDB format compatible entry.

Summary for 8RZI

• Entry DOI: 10.2210/pdb8rzi/pdb
• Descriptor: Conserved hypothetical periplasmic protein, (1~{R},4~{S},5~{S},8~{S})-4-fluoranyl-2,6-dioxabicyclo[3.2.1]octan-8-ol, L(+)-TARTARIC ACID, ... (8 entities in total)
• Functional Keywords: 3, 6-anhydro-d-galactosidase zobellia galactanivorans carrageenan oligosaccharide 3, 6-anhydro-d-galactose, hydrolase
• Biological source: Zobellia galactanivorans
• Total number of polymer chains: 4
• Total formula weight: 308120.70

Authors

Roret, T.,Czjzek, M.,Ficko-Blean, E. (deposition date: 2024-02-12, release date: 2024-07-31)

• Primary citation: Wallace, M.D.,Cuxart, I.,Roret, T.,Guee, L.,Debowski, A.W.,Czjzek, M.,Rovira, C.,Stubbs, K.A.,Ficko-Blean, E.; Constrained Catalytic Itinerary of a Retaining 3,6-Anhydro-D-Galactosidase, a Key Enzyme in Red Algal Cell Wall Degradation.; Angew.Chem.Int.Ed.Engl., :e202411171-e202411171, 2024; PubMed: 39022920; DOI: 10.1002/anie.202411171

Experimental method

X-RAY DIFFRACTION (1.96 Å)