8RY4

CryoEM structure of M. smegmatis GMP reductase in complex with GMP and GTP at pH 6.6, extended conformation II.

Summary for 8RY4

• Entry DOI: 10.2210/pdb8ry4/pdb
• Related: 8RY5
• EMDB information: 19586
• Descriptor: GMP reductase, GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE (3 entities in total)
• Functional Keywords: gmp reductase, guab1, cbs domain, mycobacterium smegmatis, oxidoreductase
• Biological source: Mycolicibacterium smegmatis
• Total number of polymer chains: 8
• Total formula weight: 421350.68

Authors

Dolezal, M.,Kouba, T.,Pichova, I. (deposition date: 2024-02-08, release date: 2025-08-20)

• Primary citation: Dolezal, M.,Knejzlik, Z.,Kouba, T.,Filimonenko, A.,Svachova, H.,Klima, M.,Pichova, I.; Structural basis for allosteric regulation of mycobacterial guanosine 5'-monophosphate reductase with ATP and GTP.; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.72 Å)