8RVK

Maltodextrin phosphorylase (MalP) in complex with a alpha-1,2-cyclophellitol analogue

This is a non-PDB format compatible entry.

Summary for 8RVK

• Entry DOI: 10.2210/pdb8rvk/pdb
• Descriptor: Maltodextrin phosphorylase, (3~{a}~{R},4~{R},5~{R},6~{R},7~{a}~{S})-6-(hydroxymethyl)-4,5-bis(oxidanyl)-3~{a},4,5,6,7,7~{a}-hexahydro-3~{H}-1,3-benzoxazol-2-one, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: phosphorylase, glycosyltransferase, gt35, carbohydrate metabolism, transferase
• Biological source: Escherichia coli K-12
• Total number of polymer chains: 2
• Total formula weight: 186434.01

Authors

Bennett, M.,Ofman, T.P.,Overkleeft, H.S.,Davies, G.J. (deposition date: 2024-02-01, release date: 2024-05-15, Last modification date: 2024-06-12)

• Primary citation: Ofman, T.P.,Heming, J.J.A.,Nin-Hill, A.,Kullmer, F.,Moran, E.,Bennett, M.,Steneker, R.,Klein, A.M.,Ruijgrok, G.,Kok, K.,Armstrong, Z.W.B.,Aerts, J.M.F.G.,van der Marel, G.A.,Rovira, C.,Davies, G.J.,Artola, M.,Codee, J.D.C.,Overkleeft, H.S.; Conformational and Electronic Variations in 1,2- and 1,5a-Cyclophellitols and their Impact on Retaining alpha-Glucosidase Inhibition.; Chemistry, 30:e202400723-e202400723, 2024; PubMed: 38623783; DOI: 10.1002/chem.202400723

Experimental method

X-RAY DIFFRACTION (2.18 Å)