8RV1

HIF prolyl hydroxylase 2 (PHD2) T387S variant bound to acetate (ACT) and hydroxylated Hypoxia-inducible Factor 2alpha (HIF2alpha)

Summary for 8RV1

• Entry DOI: 10.2210/pdb8rv1/pdb
• Descriptor: Egl nine homolog 1, Endothelial PAS domain-containing protein 1, ACETATE ION, ... (4 entities in total)
• Functional Keywords: 2og oxygenase, prolyl hydroxylase, oxygen sensing, hypoxia, oxidoreductase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 27894.56

Authors

Fiorini, G.,Schofield, C.J. (deposition date: 2024-01-31, release date: 2025-02-12)

• Primary citation: Fiorini, G.,Schofield, C.J.; investigating gatekeeper residues in prolyl hydroxyalse 2; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.39 Å)