8RI3

Crystal structure of transplatin/B-DNA adduct obtained upon 7 days of soaking

Summary for 8RI3

• Entry DOI: 10.2210/pdb8ri3/pdb
• Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION, PLATINUM (II) ION, ... (6 entities in total)
• Functional Keywords: b-dna, dodecamer, platin, interaction, dna
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 8022.87

Authors

Tito, G.,Troisi, R.,Ferraro, G.,Sica, F.,Merlino, A. (deposition date: 2023-12-18, release date: 2024-02-28)

• Primary citation: Troisi, R.,Tito, G.,Ferraro, G.,Sica, F.,Massai, L.,Geri, A.,Cirri, D.,Messori, L.,Merlino, A.; On the mechanism of action of arsenoplatins: arsenoplatin-1 binding to a B-DNA dodecamer.; Dalton Trans, 53:3476-3483, 2024; PubMed: 38270175; DOI: 10.1039/d3dt04302a

Experimental method

X-RAY DIFFRACTION (1.4 Å)