8RD7

HUWE1 WWE domain in complex with ADP-ribose

Summary for 8RD7

• Entry DOI: 10.2210/pdb8rd7/pdb
• Descriptor: E3 ubiquitin-protein ligase HUWE1, CHLORIDE ION, ACETATE ION, ... (6 entities in total)
• Functional Keywords: e3 ligase, complex, nucleotide, ligase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 42965.97

Authors

Muenzker, L.,Zak, K.M.,Boettcher, J. (deposition date: 2023-12-07, release date: 2024-07-31, Last modification date: 2024-08-07)

• Primary citation: Munzker, L.,Kimani, S.W.,Fowkes, M.M.,Dong, A.,Zheng, H.,Li, Y.,Dasovich, M.,Zak, K.M.,Leung, A.K.L.,Elkins, J.M.,Kessler, D.,Arrowsmith, C.H.,Halabelian, L.,Bottcher, J.; A ligand discovery toolbox for the WWE domain family of human E3 ligases.; Commun Biol, 7:901-901, 2024; PubMed: 39048679; DOI: 10.1038/s42003-024-06584-w

Experimental method

X-RAY DIFFRACTION (1.31 Å)