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8RD7

HUWE1 WWE domain in complex with ADP-ribose

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
E3 ubiquitin-protein ligase HUWE1polymer9110519.64UniProt (Q7Z6Z7)
Pfam (PF02825)
Homo sapiens (human)
2E, G, H, I, L
(A, B, C, D)
CHLORIDE IONnon-polymer35.55Chemie (CL)
3F
(B)
ACETATE IONnon-polymer59.01Chemie (ACT)
4J
(C)
GLYCEROLnon-polymer92.11Chemie (GOL)
5K
(D)
[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATEnon-polymer559.31Chemie (AR6)
6M, N, O, P
(A, B, C, D)
waterwater18.0431Chemie (HOH)
Sequence modifications
A, B, C, D: 1611 - 1700 (UniProt: Q7Z6Z7)
PDBExternal DatabaseDetails
Gly 1610-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight42078.3
Non-Polymers*Number of molecules8
Total formula weight887.7
All*Total formula weight42966.0
*Water molecules are not included.

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PDB entries from 2025-07-16

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