8RB2

The crystal structure of DNA-bound human MutSbeta (MSH2_E749A/MSH3_E976A) in the canonical mismatch bound conformation with ADP bound in MSH2

Summary for 8RB2

Entry DOI	10.2210/pdb8rb2/pdb
Descriptor	DNA mismatch repair protein Msh2, GLYCEROL, DNA mismatch repair protein Msh3, ... (11 entities in total)
Functional Keywords	dna repair, dna binding, dna binding protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	8
Total formula weight	497141.59
Authors	Thomsen, M.,Costanzi, E. (deposition date: 2023-12-01, release date: 2025-06-11)
Primary citation	Thomsen, M.,Neudegger, T.,Thieulin-Pardo, G.,Blaesse, M.,Costanzi, E.,Steinbacher, S.,Plotnikov, N.V.,Dominguez, C.,Iyer, R.R.,Wilkinson, H.A.,Monteagudo, E.,Haque, T.S.,Prasad, B.C.,Finley, M.,Boudet, J.,Vogt, T.F.,Felsenfeld, D.P. The crystal structure of DNA-bound human MutSbeta (MSH2/MSH3) in the canonical mismatch bound conformation with ADP bound in MSH2 and MSH3 To Be Published,
Experimental method	X-RAY DIFFRACTION (2.526 Å)

Structure validation