8RB1
The crystal structure of DNA-bound human MutSbeta (MSH2_K675R/MSH3_K902R) in the canonical mismatch bound conformation with ADP bound in MSH2 and MSH3
Summary for 8RB1
| Entry DOI | 10.2210/pdb8rb1/pdb |
| Descriptor | DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, DNA (5'-D(*TP*CP*TP*AP*TP*CP*TP*GP*AP*AP*GP*CP*CP*GP*AP*TP*CP*GP*AP*TP*GP*G)-3'), ... (10 entities in total) |
| Functional Keywords | dna repair, dna binding, dna binding protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 225718.40 |
| Authors | |
| Primary citation | Thomsen, M.,Neudegger, T.,Thieulin-Pardo, G.,Blaesse, M.,Costanzi, E.,Steinbacher, S.,Plotnikov, N.V.,Dominguez, C.,Iyer, R.R.,Wilkinson, H.A.,Monteagudo, E.,Haque, T.S.,Prasad, B.C.,Finley, M.,Boudet, J.,Vogt, T.F.,Felsenfeld, D.P. The crystal structure of DNA-bound human MutSbeta (MSH2/MSH3) in the canonical mismatch bound conformation with ADP bound in MSH2 and MSH3 To Be Published, |
| Experimental method | X-RAY DIFFRACTION (2.085 Å) |
Structure validation
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