8RAU

The crystal structure of DNA-bound human MutSbeta (MSH2/MSH3) in the canonical mismatch bound conformation with ADP bound in MSH2 and MSH3

Summary for 8RAU

• Entry DOI: 10.2210/pdb8rau/pdb
• Descriptor: DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, DNA (5'-D(*TP*CP*TP*AP*TP*CP*TP*GP*AP*AP*GP*CP*CP*GP*AP*TP*CP*GP*AP*TP*GP*G)-3'), ... (8 entities in total)
• Functional Keywords: dna repair, dna binding, dna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 225328.67

Authors

Thomsen, M.,Costanzi, E. (deposition date: 2023-12-01, release date: 2025-06-11)

• Primary citation: Thomsen, M.,Neudegger, T.,Thieulin-Pardo, G.,Blaesse, M.,Costanzi, E.,Steinbacher, S.,Plotnikov, N.V.,Dominguez, C.,Iyer, R.R.,Wilkinson, H.A.,Monteagudo, E.,Haque, T.S.,Prasad, B.C.,Finley, M.,Boudet, J.,Vogt, T.F.,Felsenfeld, D.P.; The crystal structure of DNA-bound human MutSbeta (MSH2/MSH3) in the canonical mismatch bound conformation with ADP bound in MSH2 and MSH3; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.33 Å)