8R8Q

Lysosomal peptide transporter

Summary for 8R8Q

Entry DOI	10.2210/pdb8r8q/pdb
EMDB information	19006
Descriptor	Major facilitator superfamily domain-containing protein 1, Glycosylated lysosomal membrane protein, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	mfs transporter, mfsd family, nutrition transporter, lysosomal transporter, outward open, membrane protein
Biological source	Mus musculus (house mouse) More
Total number of polymer chains	2
Total formula weight	99974.30
Authors	Jungnickel, K.E.J.,Loew, C. (deposition date: 2023-11-29, release date: 2024-05-01, Last modification date: 2024-06-12)
Primary citation	Jungnickel, K.E.J.,Guelle, O.,Iguchi, M.,Dong, W.,Kotov, V.,Gabriel, F.,Debacker, C.,Dairou, J.,McCort-Tranchepain, I.,Laqtom, N.N.,Chan, S.H.,Ejima, A.,Sato, K.,Massa Lopez, D.,Saftig, P.,Mehdipour, A.R.,Abu-Remaileh, M.,Gasnier, B.,Low, C.,Damme, M. MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes Nature Cell Biology, 2024 Cited by DOI: 10.1038/s41556-024-01436-5 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.08 Å)

Structure validation