8R8Q
Lysosomal peptide transporter
Summary for 8R8Q
Entry DOI | 10.2210/pdb8r8q/pdb |
EMDB information | 19006 |
Descriptor | Major facilitator superfamily domain-containing protein 1, Glycosylated lysosomal membrane protein, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | mfs transporter, mfsd family, nutrition transporter, lysosomal transporter, outward open, membrane protein |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 99974.30 |
Authors | Jungnickel, K.E.J.,Loew, C. (deposition date: 2023-11-29, release date: 2024-05-01, Last modification date: 2024-07-24) |
Primary citation | Jungnickel, K.E.J.,Guelle, O.,Iguchi, M.,Dong, W.,Kotov, V.,Gabriel, F.,Debacker, C.,Dairou, J.,McCort-Tranchepain, I.,Laqtom, N.N.,Chan, S.H.,Ejima, A.,Sato, K.,Massa Lopez, D.,Saftig, P.,Mehdipour, A.R.,Abu-Remaileh, M.,Gasnier, B.,Low, C.,Damme, M. MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes. Nat.Cell Biol., 26:1047-1061, 2024 Cited by PubMed: 38839979DOI: 10.1038/s41556-024-01436-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.08 Å) |
Structure validation
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