8R8Q
Lysosomal peptide transporter
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005764 | cellular_component | lysosome |
| A | 0005765 | cellular_component | lysosomal membrane |
| A | 0016020 | cellular_component | membrane |
| A | 0035442 | biological_process | dipeptide transmembrane transport |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0050821 | biological_process | protein stabilization |
| A | 0061462 | biological_process | protein localization to lysosome |
| A | 0141204 | biological_process | dipeptide transmembrane transport from lysosomal lumen to cytosol |
| A | 0160178 | molecular_function | dipeptide uniporter activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 334 |
| Details | TOPO_DOM: Lumenal => ECO:0000255 |
| Chain | Residue | Details |
| B | GLU36-GLY370 | |
| A | LEU360-VAL380 | |
| A | PHE391-LEU411 | |
| A | LEU417-LEU437 | |
| A | LEU82-ILE102 | |
| A | THR112-PHE132 | |
| A | ALA134-VAL154 | |
| A | LEU190-LEU210 | |
| A | LEU214-LEU234 | |
| A | LEU265-LEU285 | |
| A | ALA303-VAL323 | |
| A | ILE330-THR350 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| B | ILE371-LEU391 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| B | ASN64 | |
| B | ASN166 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 5 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:32959924 |
| Chain | Residue | Details |
| B | ASN85 | |
| B | ASN94 | |
| B | ASN157 | |
| B | ASN228 | |
| B | ASN331 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19349973, ECO:0000269|PubMed:32959924 |
| Chain | Residue | Details |
| B | ASN133 | |
| B | ASN185 |
