8R7V

MutSbeta bound to compound CHDI-00898647 in the canonical DNA-mismatch bound form

Summary for 8R7V

• Entry DOI: 10.2210/pdb8r7v/pdb
• EMDB information: 18992
• Descriptor: DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, DNA_61bp_Complement_Rev, ... (8 entities in total)
• Functional Keywords: dna repair, mismatch recognition, abc family atpase, proteros biostructures gmbh, dna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 272378.58

Authors

Haque, T.,Brace, G.,Felsenfeld, D.,Tilack, K.,Schaertl, S.,Ballantyne, G.,Maillard, M.,Iyer, R.,Prasad, B.,Thomsen, M.,Wilkionson, H.,Plotnikov, N.,Ritzefeld, M. (deposition date: 2023-11-27, release date: 2024-10-30)

• Primary citation: Haque, T.,Brace, G.; Identification of orthosteric inhibitors of MutSbeta ATPase function; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.12 Å)