8R3L
Influenza A/H7N9 polymerase in pre-initiation state, intermediate conformation (I) with PB2-C(I), ENDO(T), and Pol II pS5 CTD peptide mimic bound in site 1A/2A
Summary for 8R3L
Entry DOI | 10.2210/pdb8r3l/pdb |
EMDB information | 18872 |
Descriptor | Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ... (5 entities in total) |
Functional Keywords | viral polymerase, viral protein |
Biological source | Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)) More |
Total number of polymer chains | 6 |
Total formula weight | 296738.89 |
Authors | |
Primary citation | Krischuns, T.,Arragain, B.,Isel, C.,Paisant, S.,Budt, M.,Wolff, T.,Cusack, S.,Naffakh, N. The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15:1064-1064, 2024 Cited by PubMed: 38316757DOI: 10.1038/s41467-024-45205-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.25 Å) |
Structure validation
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