8R3L

Influenza A/H7N9 polymerase in pre-initiation state, intermediate conformation (I) with PB2-C(I), ENDO(T), and Pol II pS5 CTD peptide mimic bound in site 1A/2A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0004519	molecular_function	endonuclease activity
A	0006351	biological_process	DNA-templated transcription
A	0030430	cellular_component	host cell cytoplasm
A	0039523	biological_process	symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
A	0039694	biological_process	viral RNA genome replication
A	0042025	cellular_component	host cell nucleus
A	0046872	molecular_function	metal ion binding
A	0075523	biological_process	viral translational frameshifting
A	0075526	biological_process	cap snatching
B	0000166	molecular_function	nucleotide binding
B	0001172	biological_process	RNA-templated transcription
B	0003723	molecular_function	RNA binding
B	0003968	molecular_function	RNA-dependent RNA polymerase activity
B	0005737	cellular_component	cytoplasm
B	0006351	biological_process	DNA-templated transcription
B	0019083	biological_process	viral transcription
B	0030430	cellular_component	host cell cytoplasm
B	0039523	biological_process	symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
B	0039694	biological_process	viral RNA genome replication
B	0042025	cellular_component	host cell nucleus
B	0046872	molecular_function	metal ion binding
C	0001172	biological_process	RNA-templated transcription
C	0003723	molecular_function	RNA binding
C	0003968	molecular_function	RNA-dependent RNA polymerase activity
C	0006351	biological_process	DNA-templated transcription
C	0006370	biological_process	7-methylguanosine mRNA capping
C	0019083	biological_process	viral transcription
C	0033650	cellular_component	host cell mitochondrion
C	0039523	biological_process	symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
C	0039694	biological_process	viral RNA genome replication
C	0042025	cellular_component	host cell nucleus
C	0044423	cellular_component	virion component
C	0075526	biological_process	cap snatching
G	0003677	molecular_function	DNA binding
G	0006366	biological_process	transcription by RNA polymerase II

Functional Information from PROSITE/UniProt

site_id	PS00115
Number of Residues	7
Details	RNA_POL_II_REPEAT Eukaryotic RNA polymerase II heptapeptide repeat. YSPTSPS

Chain	Residue	Details
G	TYR3-SER9
G	TYR10-SER16
G	TYR17-SER23
G	TYR24-SER30
G	TYR31-SER37
G	TYR38-SER44

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