8R21

Alpha-1-antitrypsin (Ile340Trp) in the native conformation

This is a non-PDB format compatible entry.

Summary for 8R21

• Entry DOI: 10.2210/pdb8r21/pdb
• Related: 6I7U 8QZ5
• Descriptor: Alpha-1-antitrypsin (2 entities in total)
• Functional Keywords: antitrypsin, protease inhibitor, serpin, mutant, deficiency, small molecule, protein binding
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 91369.59

Authors

Aldobiyan, I.,Lee, H.J.,Lomas, D.A.,Irving, J.A. (deposition date: 2023-11-02, release date: 2024-11-13)

• Primary citation: Aldobiyan, I.,Lee, H.J.,Irving, J.A.,Lomas, D.A.; Structural determinants of instability in alpha-1-antitrypsin; To be published,

Experimental method

X-RAY DIFFRACTION (2.88 Å)