8R21

Alpha-1-antitrypsin (Ile340Trp) in the native conformation

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Alpha-1-antitrypsin	polymer	404	45684.8	2	UniProt (P01009) Pfam (PF00079)	Homo sapiens (human)
2	C, D (A, B)	water	water		18.0	10	Chemie (HOH)

Sequence modifications

A, B: 2 - 394 (UniProt: P01009)

PDB	External Database	Details
Met -9	-	initiating methionine
Arg -8	-	expression tag
Gly -7	-	expression tag
Ser -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Thr 1	-	expression tag
Trp 340	Ile 364	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	91369.6
All*	Total formula weight	91369.6

*Water molecules are not included.