8R1L

Structure of avian H5N1 influenza A polymerase in complex with human ANP32B.

Summary for 8R1L

• Entry DOI: 10.2210/pdb8r1l/pdb
• EMDB information: 18822
• Descriptor: Acidic leucine-rich nuclear phosphoprotein 32 family member B, Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, ... (4 entities in total)
• Functional Keywords: influenza virus, replication platform, h5n1, influenza adaptive mutations, host adaptation, viral polymerase, cryo-em, hpai., viral protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 299413.26

Authors

Carrique, L.,Staller, E.,Keown, J.R.,Fan, H.,Fodor, E.,Grimes, J.M. (deposition date: 2023-11-02, release date: 2024-05-08, Last modification date: 2024-07-24)

• Primary citation: Kefauver, J.M.,Hakala, M.,Zou, L.,Alba, J.,Espadas Moreno, J.,Tettamanti, M.G.,Estrozi, L.,Vanni, S.,Roux, A.,Desfosses, A.,Loewith, R.; CryoEM architecture of a native stretch-sensitive membrane microdomain; To Be Published, ; DOI: 10.1038/s41586-024-07720-6

Experimental method

ELECTRON MICROSCOPY (3.1 Å)