8R1L

Structure of avian H5N1 influenza A polymerase in complex with human ANP32B.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0016787	molecular_function	hydrolase activity
A	0039523	biological_process	symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
A	0039657	biological_process	symbiont-mediated suppression of host gene expression
A	0039694	biological_process	viral RNA genome replication
A	0046872	molecular_function	metal ion binding
A	0075523	biological_process	viral translational frameshifting
A	0075526	biological_process	cap snatching
B	0000166	molecular_function	nucleotide binding
B	0001172	biological_process	RNA-templated transcription
B	0003723	molecular_function	RNA binding
B	0003968	molecular_function	RNA-directed RNA polymerase activity
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0019083	biological_process	viral transcription
B	0030430	cellular_component	host cell cytoplasm
B	0034062	molecular_function	5'-3' RNA polymerase activity
B	0039523	biological_process	symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
B	0039657	biological_process	symbiont-mediated suppression of host gene expression
B	0039694	biological_process	viral RNA genome replication
B	0042025	cellular_component	host cell nucleus
C	0003723	molecular_function	RNA binding
C	0006351	biological_process	DNA-templated transcription
C	0006370	biological_process	7-methylguanosine mRNA capping
C	0006397	biological_process	mRNA processing
C	0019083	biological_process	viral transcription
C	0019865	molecular_function	immunoglobulin binding
C	0033650	cellular_component	host cell mitochondrion
C	0039523	biological_process	symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
C	0039657	biological_process	symbiont-mediated suppression of host gene expression
C	0039694	biological_process	viral RNA genome replication
C	0042025	cellular_component	host cell nucleus
C	0044423	cellular_component	virion component
C	0075526	biological_process	cap snatching
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005730	cellular_component	nucleolus
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006334	biological_process	nucleosome assembly
D	0042393	molecular_function	histone binding
D	0042981	biological_process	regulation of apoptotic process
D	0043066	biological_process	negative regulation of apoptotic process
D	0045596	biological_process	negative regulation of cell differentiation
D	0046827	biological_process	positive regulation of protein export from nucleus
D	0070062	cellular_component	extracellular exosome
D	0070063	molecular_function	RNA polymerase binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	Repeat: {"description":"LRR 1","evidences":[{"source":"PubMed","id":"20538007","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	21
Details	Repeat: {"description":"LRR 2","evidences":[{"source":"PubMed","id":"20538007","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	19
Details	Repeat: {"description":"LRR 3","evidences":[{"source":"PubMed","id":"20538007","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	21
Details	Repeat: {"description":"LRR 4","evidences":[{"source":"PubMed","id":"20538007","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9EST6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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