8R0Z

14-3-3 sigma in complex with TAZ peptide and stabilizing fragment TCF199

Summary for 8R0Z

• Entry DOI: 10.2210/pdb8r0z/pdb
• Descriptor: 14-3-3 protein sigma, WW domain-containing transcription regulator protein 1, [(4aR,8aR)-2,3,4,5,6,7,8,8a-octahydro-1H-quinolin-4a-yl]methyl N-phenylcarbamate, ... (5 entities in total)
• Functional Keywords: protein complex, stabilization, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 29722.94

Authors

Centorrino, F.,Andlovic, B.,Ottmann, C. (deposition date: 2023-11-01, release date: 2024-09-04)

• Primary citation: Andlovic, B.,Valenti, D.,Centorrino, F.,Picarazzi, F.,Hristeva, S.,Hiltmann, M.,Wolf, A.,Cantrelle, F.X.,Mori, M.,Landrieu, I.,Levy, L.M.,Klebl, B.,Tzalis, D.,Genski, T.,Eickhoff, J.,Ottmann, C.; Fragment-Based Interrogation of the 14-3-3/TAZ Protein-Protein Interaction.; Biochemistry, 2024; PubMed: 39172504; DOI: 10.1021/acs.biochem.4c00248

Experimental method

X-RAY DIFFRACTION (1.2 Å)