8R0H

Pim1 in complex with (E)-3-(2-(thiophen-2-yl)vinyl)-3,4-dihydroquinoxalin-2(1H)-one and Pimtide

Summary for 8R0H

• Entry DOI: 10.2210/pdb8r0h/pdb
• Related: 7QB2 7QFM 7Z6U 8AFR
• Descriptor: Serine/threonine-protein kinase pim-1, Pimtide, GLYCEROL, ... (5 entities in total)
• Functional Keywords: serine kinase, kinase, complex, pim1, pim, pim-1, inhibitor, tumorigenisis, cancer, pimtide, proto oncogen, atp, phosphorylation, apoptosis, cell cycle, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 37701.82

Authors

Hochban, P.M.M.,Heine, A.,Diederich, W.E. (deposition date: 2023-10-31, release date: 2024-11-13)

• Primary citation: Hochban, P.M.M.,Heyder, L.,Heine, A.,Diederich, W.E.; Pim1 in complex with (E)-3-(2-(thiophen-2-yl)vinyl)-3,4-dihydroquinoxalin-2(1H)-one and Pimtide; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.88 Å)