8QVW

Cryo-EM structure of the peptide binding domain of human SRP68/72

Summary for 8QVW

Entry DOI	10.2210/pdb8qvw/pdb
EMDB information	18674
Descriptor	Signal recognition particle subunit SRP68, Signal recognition particle subunit SRP72 (2 entities in total)
Functional Keywords	signal recognition particle, tpr, protein translocation, translation
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	141609.84
Authors	Zhong, Y.,Feng, J.,Koh, A.F.,Kotecha, A.,Greber, B.J.,Ataide, S.F. (deposition date: 2023-10-18, release date: 2024-02-07, Last modification date: 2024-08-21)
Primary citation	Zhong, Y.,Feng, J.,Koh, A.F.,Kotecha, A.,Greber, B.J.,Ataide, S.F. Cryo-EM structure of SRP68/72 reveals an extended dimerization domain with RNA-binding activity. Nucleic Acids Res., 52:5285-5300, 2024 Cited by PubMed: 38366771 DOI: 10.1093/nar/gkae107 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3 Å)

Structure validation