8QQG

Structure of BRAF in Complex With Exarafenib (KIN-2787).

Summary for 8QQG

• Entry DOI: 10.2210/pdb8qqg/pdb
• Descriptor: Serine/threonine-protein kinase B-raf, (3~{S})-~{N}-[4-methyl-3-[2-morpholin-4-yl-6-[[(2~{R})-1-oxidanylpropan-2-yl]amino]pyridin-4-yl]phenyl]-3-[2,2,2-tris(fluoranyl)ethyl]pyrrolidine-1-carboxamide, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: transferase, braf
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 95866.88

Authors

Schmitt, A.,Costanzi, E.,Kania, R.,Chen, Y.K. (deposition date: 2023-10-04, release date: 2024-01-24)

• Primary citation: Schmitt, A.,Costanzi, E.,Kania, R.,Chen, Y.K.; Structure of BRAF in Complex With Exarafenib (KIN-2787).; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.979 Å)