8QQG
Structure of BRAF in Complex With Exarafenib (KIN-2787).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Serine/threonine-protein kinase B-raf | polymer | 275 | 31351.3 | 3 | UniProt (P15056) Pfam (PF07714) | Homo sapiens (human) | Proto-oncogene B-Raf,p94,v-Raf murine sarcoma viral oncogene homolog B1 |
| 2 | D, H, K (A, B, C) | Exarafenib | non-polymer | 521.6 | 3 | Chemie (WJ9) PubChem (156297486) PubChem (156297488) PubChem (156297592) PubChem (162468163) PubChem (162468170) PubChem (166758633) | |||
| 3 | E, F, G, I, J... (A, B, C) | CHLORIDE ION | non-polymer | 35.5 | 7 | Chemie (CL) PubChem (312) | |||
| 4 | N, O, P (A, B, C) | water | water | 18.0 | 80 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 94054.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1812.9 | |
| All* | Total formula weight | 95866.9 |
