8QOD

CRYSTAL STRUCTURE OF FVIIA IN COMPLEX WITH A BENZAMIDINE-BASED INHIBITOR

Summary for 8QOD

• Entry DOI: 10.2210/pdb8qod/pdb
• Descriptor: Factor VII light chain, Coagulation factor VII, Tissue factor, ... (10 entities in total)
• Functional Keywords: inhibitor complex, blood clotting
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 72843.76

Authors

Schreuder, H.A.,Liesum, A. (deposition date: 2023-09-28, release date: 2024-10-09)

• Primary citation: Tesmer, L.,Hans Matter, H.,Klingler, O.,Schudok, M.,Hessler, G.,Mehdipour, A.R.,Guessregen, S.,Hummer, G.,Schreuder, H.A.; Crystallography and molecular simulations capture S1 pocket collapse in allosteric regulation of factor VIIa and other serine proteases.; To be published,

Experimental method

X-RAY DIFFRACTION (1.573 Å)