8QOD
CRYSTAL STRUCTURE OF FVIIA IN COMPLEX WITH A BENZAMIDINE-BASED INHIBITOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Factor VII light chain | polymer | 141 | 16303.8 | 1 | UniProt (P08709) Pfam (PF00594) Pfam (PF00008) Pfam (PF14670) | Homo sapiens (human) | |
| 2 | B (B) | Coagulation factor VII | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) | Homo sapiens (human) | Proconvertin,Serum prothrombin conversion accelerator,SPCA |
| 3 | C (C) | Tissue factor | polymer | 243 | 27297.5 | 1 | UniProt (P13726) Pfam (PF01108) Pfam (PF09294) | Homo sapiens (human) | TF,Coagulation factor III,Thromboplastin |
| 4 | D, H, I, K (A, B) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F (A) | alpha-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (GLC) | |||
| 7 | G (A) | alpha-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUC) | |||
| 8 | J (B) | 3-[2-bromanyl-4-[(1~{S})-1-[[3-[(4-carbamimidoylphenyl)amino]-3-oxidanylidene-propanoyl]amino]ethyl]phenoxy]benzoic acid | non-polymer | 539.4 | 1 | Chemie (WIZ) | |||
| 9 | L, M (B, C) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 10 | N, O, P (A, B, C) | water | water | 18.0 | 1092 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 71704.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1139.2 | |
| All* | Total formula weight | 72843.8 |
