8QMS

Succinic semialdehyde dehydrogenase from E. coli with Q262R substitution and bound NAD+

Summary for 8QMS

• Entry DOI: 10.2210/pdb8qms/pdb
• Descriptor: Succinate semialdehyde dehydrogenase [NAD(P)+] Sad, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
• Functional Keywords: succinic semialdehyde, dehydrogenase, oxidoreductase
• Biological source: Escherichia coli K-12
• Total number of polymer chains: 4
• Total formula weight: 201848.72

Authors

He, H.,Zarzycki, J.,Erb, T.J. (deposition date: 2023-09-25, release date: 2024-10-02)

• Primary citation: He, H.,Gomez-Coronado, P.A.,Zarzycki, J.,Barthel, S.,Kahnt, J.,Claus, P.,Klein, M.,Klose, M.,de Crecy-Lagard, V.,Schindler, D.,Paczia, N.,Glatter, T.,Erb, T.J.; Adaptive laboratory evolution recruits the promiscuity of succinate semialdehyde dehydrogenase to repair different metabolic deficiencies; Nat Commun, 2024

Experimental method

X-RAY DIFFRACTION (1.9 Å)